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Interferon-driven alterations of the host’s amino acid metabolism in the pathogenesis of typhoid fever
Enteric fever, caused by Salmonella enterica serovar Typhi, is an important public health problem in resource-limited settings and, despite decades of research, human responses to the infection are poorly understood. In 41 healthy adults experimentally infected with wild-type S. Typhi, we detected s...
Autores principales: | Blohmke, Christoph J., Darton, Thomas C., Jones, Claire, Suarez, Nicolas M., Waddington, Claire S., Angus, Brian, Zhou, Liqing, Hill, Jennifer, Clare, Simon, Kane, Leanne, Mukhopadhyay, Subhankar, Schreiber, Fernanda, Duque-Correa, Maria A., Wright, James C., Roumeliotis, Theodoros I., Yu, Lu, Choudhary, Jyoti S., Mejias, Asuncion, Ramilo, Octavio, Shanyinde, Milensu, Sztein, Marcelo B., Kingsley, Robert A., Lockhart, Stephen, Levine, Myron M., Lynn, David J., Dougan, Gordon, Pollard, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886356/ https://www.ncbi.nlm.nih.gov/pubmed/27217537 http://dx.doi.org/10.1084/jem.20151025 |
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