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Interferon-γ facilitates hepatic antiviral T cell retention for the maintenance of liver-induced systemic tolerance

Persistent exposure to liver pathogens leads to systemic antigen-specific tolerance, a major cause of chronicity during hepatotropic infection. The mechanism regarding how this systemic tolerance is maintained remains poorly elucidated. In a well established mouse model of hepatitis B virus (HBV) pe...

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Detalles Bibliográficos
Autores principales: Zeng, Zhutian, Li, Lu, Chen, Yongyan, Wei, Haiming, Sun, Rui, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886358/
https://www.ncbi.nlm.nih.gov/pubmed/27139489
http://dx.doi.org/10.1084/jem.20151218