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Interferon-γ facilitates hepatic antiviral T cell retention for the maintenance of liver-induced systemic tolerance
Persistent exposure to liver pathogens leads to systemic antigen-specific tolerance, a major cause of chronicity during hepatotropic infection. The mechanism regarding how this systemic tolerance is maintained remains poorly elucidated. In a well established mouse model of hepatitis B virus (HBV) pe...
Autores principales: | Zeng, Zhutian, Li, Lu, Chen, Yongyan, Wei, Haiming, Sun, Rui, Tian, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886358/ https://www.ncbi.nlm.nih.gov/pubmed/27139489 http://dx.doi.org/10.1084/jem.20151218 |
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