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Local antigen in nonlymphoid tissue promotes resident memory CD8(+) T cell formation during viral infection

Tissue-resident memory (Trm) CD8(+) T cells are functionally distinct from their circulating counterparts and are potent mediators of host protection against reinfection. Whether local recognition of antigen in nonlymphoid tissues during infection can impact the formation of Trm populations remains...

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Detalles Bibliográficos
Autores principales: Khan, Tahsin N., Mooster, Jana L., Kilgore, Augustus M., Osborn, Jossef F., Nolz, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886364/
https://www.ncbi.nlm.nih.gov/pubmed/27217536
http://dx.doi.org/10.1084/jem.20151855