Cargando…
Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development
The generation of high-affinity antibodies requires germinal center (GC) development and differentiation of long-lived plasma cells in a multilayered process that is tightly controlled by the activity of multiple transcription factors. Here, we reveal a new layer of complexity by demonstrating that...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886367/ https://www.ncbi.nlm.nih.gov/pubmed/27217539 http://dx.doi.org/10.1084/jem.20152003 |