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Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development
The generation of high-affinity antibodies requires germinal center (GC) development and differentiation of long-lived plasma cells in a multilayered process that is tightly controlled by the activity of multiple transcription factors. Here, we reveal a new layer of complexity by demonstrating that...
Autores principales: | Gloury, Renee, Zotos, Dimitra, Zuidscherwoude, Malou, Masson, Frederick, Liao, Yang, Hasbold, Jhaguaral, Corcoran, Lynn M., Hodgkin, Phil D., Belz, Gabrielle T., Shi, Wei, Nutt, Stephen L., Tarlinton, David M., Kallies, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886367/ https://www.ncbi.nlm.nih.gov/pubmed/27217539 http://dx.doi.org/10.1084/jem.20152003 |
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