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The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

BACKGROUND: Recent vaccine studies have shown that the magnitude of an antibody response is often insufficient to explain efficacy, suggesting that characteristics regarding the quality of the antibody response, such as its fine specificity and functional activity, may play a major role in protectio...

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Detalles Bibliográficos
Autores principales: Chaudhury, Sidhartha, Ockenhouse, Christian F., Regules, Jason A., Dutta, Sheetij, Wallqvist, Anders, Jongert, Erik, Waters, Norman C., Lemiale, Franck, Bergmann-Leitner, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886414/
https://www.ncbi.nlm.nih.gov/pubmed/27245446
http://dx.doi.org/10.1186/s12936-016-1348-9