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The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity
BACKGROUND: Recent vaccine studies have shown that the magnitude of an antibody response is often insufficient to explain efficacy, suggesting that characteristics regarding the quality of the antibody response, such as its fine specificity and functional activity, may play a major role in protectio...
Autores principales: | Chaudhury, Sidhartha, Ockenhouse, Christian F., Regules, Jason A., Dutta, Sheetij, Wallqvist, Anders, Jongert, Erik, Waters, Norman C., Lemiale, Franck, Bergmann-Leitner, Elke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886414/ https://www.ncbi.nlm.nih.gov/pubmed/27245446 http://dx.doi.org/10.1186/s12936-016-1348-9 |
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