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A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation

In vitro liver models have been important tools for more than 40 years for academic research and preclinical toxicity screening by the pharmaceutical industry. Hepatocytes, the highly metabolic parenchymal cells of the liver, are efficient at different metabolic chemistries depending on their relati...

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Detalles Bibliográficos
Autores principales: McCarty, William J., Usta, O. Berk, Yarmush, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886516/
https://www.ncbi.nlm.nih.gov/pubmed/27240736
http://dx.doi.org/10.1038/srep26868