A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative

Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo. Despite its popularity, the use of blebbistatin is hindered by its poor water-solubility (below 10 micromolar in aqueous buffer) and blue-light sensitivity, resulting i...

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Detalles Bibliográficos
Autores principales: Várkuti, Boglárka H., Képiró, Miklós, Horváth, István Ádám, Végner, László, Ráti, Szilvia, Zsigmond, Áron, Hegyi, György, Lenkei, Zsolt, Varga, Máté, Málnási-Csizmadia, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886532/
https://www.ncbi.nlm.nih.gov/pubmed/27241904
http://dx.doi.org/10.1038/srep26141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886532/
https://www.ncbi.nlm.nih.gov/pubmed/27241904
http://dx.doi.org/10.1038/srep26141

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