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A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo. Despite its popularity, the use of blebbistatin is hindered by its poor water-solubility (below 10 micromolar in aqueous buffer) and blue-light sensitivity, resulting i...
Autores principales: | Várkuti, Boglárka H., Képiró, Miklós, Horváth, István Ádám, Végner, László, Ráti, Szilvia, Zsigmond, Áron, Hegyi, György, Lenkei, Zsolt, Varga, Máté, Málnási-Csizmadia, András |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886532/ https://www.ncbi.nlm.nih.gov/pubmed/27241904 http://dx.doi.org/10.1038/srep26141 |
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