Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation

In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity. Although much is known about the development of fibrosis and chronic inflammation in muscular dystrophy, less is known about how they are mecha...

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Detalles Bibliográficos
Autores principales: Arecco, N., Clarke, C. J., Jones, F. K., Simpson, D. M., Mason, D., Beynon, R. J., Pisconti, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886533/
https://www.ncbi.nlm.nih.gov/pubmed/27241590
http://dx.doi.org/10.1038/srep24708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886533/
https://www.ncbi.nlm.nih.gov/pubmed/27241590
http://dx.doi.org/10.1038/srep24708

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