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Silent Synapse-Based Circuitry Remodeling in Drug Addiction

Exposure to cocaine, and likely other drugs of abuse, generates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-silent glutamatergic synapses in the nucleus accumbens. These immature synaptic contacts evolve after drug withdrawal to redefine the neurocircuital properties. These results...

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Detalles Bibliográficos
Autor principal: Dong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886671/
https://www.ncbi.nlm.nih.gov/pubmed/26721952
http://dx.doi.org/10.1093/ijnp/pyv136