Proteasome activity is required for the initiation of precancerous pancreatic lesions

Proteasome activity is significantly increased in advanced cancers, but its role in cancer initiation is not clear, due to difficulties in monitoring this process in vivo. We established a line of transgenic mice that carried the ZsGreen-degron(ODC) (Gdeg) proteasome reporter to monitor the proteaso...

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Detalles Bibliográficos
Autores principales: Furuyama, Takaki, Tanaka, Shinji, Shimada, Shu, Akiyama, Yoshimitsu, Matsumura, Satoshi, Mitsunori, Yusuke, Aihara, Arihiro, Ban, Daisuke, Ochiai, Takanori, Kudo, Atsushi, Fukamachi, Hiroshi, Arii, Shigeki, Kawaguchi, Yoshiya, Tanabe, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886684/
https://www.ncbi.nlm.nih.gov/pubmed/27244456
http://dx.doi.org/10.1038/srep27044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886684/
https://www.ncbi.nlm.nih.gov/pubmed/27244456
http://dx.doi.org/10.1038/srep27044

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