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LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia

Compelling evidence suggests that benign prostatic hyperplasia (BPH) development involves accumulation of mesenchymal-like cells derived from the prostatic epithelium by epithelial-mesenchymal transition (EMT). Transforming growth factor (TGF)-β induces EMT phenotypes with low E-cadherin and high vi...

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Detalles Bibliográficos
Autores principales: He, Yao, Ou, Zhenyu, Chen, Xiang, Zu, Xiongbing, Liu, Longfei, Li, Yuan, Cao, Zhenzhen, Chen, Minfeng, Chen, Zhi, Chen, Hequn, Qi, Lin, Wang, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886686/
https://www.ncbi.nlm.nih.gov/pubmed/27243216
http://dx.doi.org/10.1038/srep27051