Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression

Inflammation may be maladaptive to the control of viral infection when it impairs interferon (IFN) responses, enhancing viral replication and spread. Dysregulated immunity as a result of inappropriate innate inflammatory responses is a hallmark of chronic viral infections such as, hepatitis B virus...

Descripción completa

Detalles Bibliográficos
Autores principales: MacParland, Sonya A., Ma, Xue-Zhong, Chen, Limin, Khattar, Ramzi, Cherepanov, Vera, Selzner, Markus, Feld, Jordan J., Selzner, Nazia, McGilvray, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886784/
https://www.ncbi.nlm.nih.gov/pubmed/27009955
http://dx.doi.org/10.1128/JVI.02557-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886784/
https://www.ncbi.nlm.nih.gov/pubmed/27009955
http://dx.doi.org/10.1128/JVI.02557-15

Ejemplares similares