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Characterization of the mammalian family of DCN-type NEDD8 E3 ligases

Cullin-RING ligases (CRL) are ubiquitin E3 enzymes that bind substrates through variable substrate receptor proteins and are activated by attachment of the ubiquitin-like protein NEDD8 to the cullin subunit. DCNs are NEDD8 E3 ligases that promote neddylation. Mammalian cells express five DCN-like (D...

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Detalles Bibliográficos
Autores principales: Keuss, Matthew J., Thomas, Yann, Mcarthur, Robin, Wood, Nicola T., Knebel, Axel, Kurz, Thimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886823/
https://www.ncbi.nlm.nih.gov/pubmed/26906416
http://dx.doi.org/10.1242/jcs.181784