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Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

Protein–protein interactions (PPIs) underlie most biological processes. An increasing interest to investigate the unexplored potential of PPIs in drug discovery is driven by the need to find novel therapeutic targets for a whole range of diseases with a high unmet medical need. To date, PPI inhibiti...

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Detalles Bibliográficos
Autores principales: Petta, Ioanna, Lievens, Sam, Libert, Claude, Tavernier, Jan, De Bosscher, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886928/
https://www.ncbi.nlm.nih.gov/pubmed/26675501
http://dx.doi.org/10.1038/mt.2015.214