Chronic Iron Overload Results in Impaired Bacterial Killing of THP-1 Derived Macrophage through the Inhibition of Lysosomal Acidification

Iron is essential for living organisms and the disturbance of iron homeostasis is associated with altered immune function. Additionally, bacterial infections can cause major complications in instances of chronic iron overload, such as patients with transfusion-dependent thalassemia. Monocytes and ma...

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Detalles Bibliográficos
Autores principales: Kao, Jun-Kai, Wang, Shih-Chung, Ho, Li-Wei, Huang, Shi-Wei, Chang, Shu-Hao, Yang, Rei-Cheng, Ke, Yu-Yuan, Wu, Chun-Ying, Wang, Jiu-Yao, Shieh, Jeng-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886970/
https://www.ncbi.nlm.nih.gov/pubmed/27244448
http://dx.doi.org/10.1371/journal.pone.0156713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886970/
https://www.ncbi.nlm.nih.gov/pubmed/27244448
http://dx.doi.org/10.1371/journal.pone.0156713

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