Polarity-sensitive nanocarrier for oral delivery of Sb(V) and treatment of cutaneous leishmaniasis

There is a great need for orally active drugs for the treatment of the neglected tropical disease leishmaniasis. Amphiphilic Sb(V) complexes, such as 1:3 Sb–N-octanoyl-N-methylglucamide complex (SbL8), are promising drug candidates. It has been previously reported that SbL8 forms kinetically stabili...

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Detalles Bibliográficos
Autores principales: Lanza, Juliane S, Fernandes, Flaviana R, Corrêa-Júnior, José D, Vilela, José MC, Magalhães-Paniago, Rogério, Ferreira, Lucas AM, Andrade, Margareth S, Demicheli, Cynthia, Melo, Maria N, Frézard, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887043/
https://www.ncbi.nlm.nih.gov/pubmed/27307731
http://dx.doi.org/10.2147/IJN.S105952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887043/
https://www.ncbi.nlm.nih.gov/pubmed/27307731
http://dx.doi.org/10.2147/IJN.S105952

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