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Multi-Compartmentalisation in the MAPK Signalling Pathway Contributes to the Emergence of Oscillatory Behaviour and to Ultrasensitivity

Signal transduction through the Mitogen Activated Protein Kinase (MAPK) pathways is evolutionarily highly conserved. Many cells use these pathways to interpret changes to their environment and respond accordingly. The pathways are central to triggering diverse cellular responses such as survival, ap...

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Detalles Bibliográficos
Autores principales: Shuaib, Aban, Hartwell, Adam, Kiss-Toth, Endre, Holcombe, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887093/
https://www.ncbi.nlm.nih.gov/pubmed/27243235
http://dx.doi.org/10.1371/journal.pone.0156139