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The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus Integration

Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are ubiquitous betaherpesviruses that infects humans within the first years of life and establishes latency in various cell types. Both viruses can integrate their genomes into telomeres of host chromosomes in latently infected cells. The molecular mecha...

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Detalles Bibliográficos
Autores principales: Wallaschek, Nina, Sanyal, Anirban, Pirzer, Fabian, Gravel, Annie, Mori, Yasuko, Flamand, Louis, Kaufer, Benedikt B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887096/
https://www.ncbi.nlm.nih.gov/pubmed/27244446
http://dx.doi.org/10.1371/journal.ppat.1005666