Multiplex Real-Time PCR Assays that Measure the Abundance of Extremely Rare Mutations Associated with Cancer

We describe the use of “SuperSelective” primers that enable the detection and quantitation of somatic mutations whose presence relates to cancer diagnosis, prognosis, and therapy, in real-time PCR assays that can potentially analyze rare DNA fragments present in blood samples (liquid biopsies). The...

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Detalles Bibliográficos
Autores principales: Vargas, Diana Y., Kramer, Fred Russell, Tyagi, Sanjay, Marras, Salvatore A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887114/
https://www.ncbi.nlm.nih.gov/pubmed/27244445
http://dx.doi.org/10.1371/journal.pone.0156546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887114/
https://www.ncbi.nlm.nih.gov/pubmed/27244445
http://dx.doi.org/10.1371/journal.pone.0156546

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