Cargando…

Clinical iron deficiency disturbs normal human responses to hypoxia

BACKGROUND. Iron bioavailability has been identified as a factor that influences cellular hypoxia sensing, putatively via an action on the hypoxia-inducible factor (HIF) pathway. We therefore hypothesized that clinical iron deficiency would disturb integrated human responses to hypoxia. METHODS. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Frise, Matthew C., Cheng, Hung-Yuan, Nickol, Annabel H., Curtis, M. Kate, Pollard, Karen A., Roberts, David J., Ratcliffe, Peter J., Dorrington, Keith L., Robbins, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887172/
https://www.ncbi.nlm.nih.gov/pubmed/27140401
http://dx.doi.org/10.1172/JCI85715