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Extracellular interactions and ligand degradation shape the nodal morphogen gradient

The correct distribution and activity of secreted signaling proteins called morphogens is required for many developmental processes. Nodal morphogens play critical roles in embryonic axis formation in many organisms. Models proposed to generate the Nodal gradient include diffusivity, ligand processi...

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Detalles Bibliográficos
Autores principales: Wang, Yin, Wang, Xi, Wohland, Thorsten, Sampath, Karuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887204/
https://www.ncbi.nlm.nih.gov/pubmed/27101364
http://dx.doi.org/10.7554/eLife.13879