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Extracellular interactions and ligand degradation shape the nodal morphogen gradient
The correct distribution and activity of secreted signaling proteins called morphogens is required for many developmental processes. Nodal morphogens play critical roles in embryonic axis formation in many organisms. Models proposed to generate the Nodal gradient include diffusivity, ligand processi...
Autores principales: | Wang, Yin, Wang, Xi, Wohland, Thorsten, Sampath, Karuna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887204/ https://www.ncbi.nlm.nih.gov/pubmed/27101364 http://dx.doi.org/10.7554/eLife.13879 |
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