Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication

Replisome assembly requires the loading of replicative hexameric helicases onto origins by AAA+ ATPases. How loader activity is appropriately controlled remains unclear. Here, we use structural and biochemical analyses to establish how an antimicrobial phage protein interferes with the function of t...

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Detalles Bibliográficos
Autores principales: Hood, Iris V, Berger, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887207/
https://www.ncbi.nlm.nih.gov/pubmed/27244442
http://dx.doi.org/10.7554/eLife.14158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887207/
https://www.ncbi.nlm.nih.gov/pubmed/27244442
http://dx.doi.org/10.7554/eLife.14158

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