Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration

Hyperhomocysteinemia (HHcy) accelerates atherosclerosis by increasing proliferation and stimulating cytokine secretion in T cells. However, whether homocysteine (Hcy)-mediated T cell activation is associated with metabolic reprogramming is unclear. Here, our in vivo and in vitro studies showed that...

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Detalles Bibliográficos
Autores principales: Feng, Juan, Lü, Silin, Ding, Yanhong, Zheng, Ming, Wang, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887324/
https://www.ncbi.nlm.nih.gov/pubmed/26856873
http://dx.doi.org/10.1007/s13238-016-0245-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887324/
https://www.ncbi.nlm.nih.gov/pubmed/26856873
http://dx.doi.org/10.1007/s13238-016-0245-x

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