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Poly-ubiquitination in TNFR1-mediated necroptosis

Tumor necrosis factor (TNF) is a master pro-inflammatory cytokine, and inappropriate TNF signaling is implicated in the pathology of many inflammatory diseases. Ligation of TNF to its receptor TNFR1 induces the transient formation of a primary membrane-bound signaling complex, known as complex I, th...

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Detalles Bibliográficos
Autores principales: Dondelinger, Yves, Darding, Maurice, Bertrand, Mathieu J. M., Walczak, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887548/
https://www.ncbi.nlm.nih.gov/pubmed/27066894
http://dx.doi.org/10.1007/s00018-016-2191-4