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Guizhi Fuling Wan, a Traditional Chinese Herbal Formula, Sensitizes Cisplatin-Resistant Human Ovarian Cancer Cells through Inactivation of the PI3K/AKT/mTOR Pathway

The aim of the study was to explore the possible mechanisms that Guizhi Fuling Wan (GFW) enhances the sensitivity of the SKOV3/DDP ovarian cancer cells and the resistant xenograft tumours to cisplatin. Rat medicated sera containing GFW were prepared by administering GFW to rats, and the primary bioa...

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Detalles Bibliográficos
Autores principales: Han, Li, Guo, Xiaojuan, Bian, Hua, Yang, Lei, Chen, Zhong, Zang, Wenhua, Yang, Jingke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887624/
https://www.ncbi.nlm.nih.gov/pubmed/27293459
http://dx.doi.org/10.1155/2016/4651949