Inhibitory effect of clemastine on P-glycoprotein expression and function: an in vitro and in situ study

OBJECTIVE(S): Transporters have an important role in pharmacokinetics of drugs. Inhibition or induction of drug transporters activity can affect drug absorption, safety, and efficacy. P-glycoprotein (P-gp) is the most important membrane transporter that is responsible for active efflux of drugs. It...

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Detalles Bibliográficos
Autores principales: Abbasi, Mehran Mesgari, Valizadeh, Hadi, Hamishekar, Hamed, Mohammadnejad, Leila, Zakeri-Milani, Parvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887716/
https://www.ncbi.nlm.nih.gov/pubmed/27279987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887716/
https://www.ncbi.nlm.nih.gov/pubmed/27279987

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