Targeted next-generation sequencing reveals multiple deleterious variants in OPLL-associated genes

Ossification of the posterior longitudinal ligament of the spine (OPLL), which is characterized by ectopic bone formation in the spinal ligaments, can cause spinal-cord compression. To date, at least 11 susceptibility genes have been genetically linked to OPLL. In order to identify potential deleter...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Guo, Jun, Cai, Tao, Zhang, Fengshan, Pan, Shengfa, Zhang, Li, Wang, Shaobo, Zhou, Feifei, Diao, Yinze, Zhao, Yanbin, Chen, Zhen, Liu, Xiaoguang, Chen, Zhongqiang, Liu, Zhongjun, Sun, Yu, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887887/
https://www.ncbi.nlm.nih.gov/pubmed/27246988
http://dx.doi.org/10.1038/srep26962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887887/
https://www.ncbi.nlm.nih.gov/pubmed/27246988
http://dx.doi.org/10.1038/srep26962

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