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Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods

Phosphoinositides play important roles in numerous intracellular membrane pathways. Little is known about the regulation or function of these lipids in rod photoreceptor cells, which have highly active membrane dynamics. Using new assays with femtomole sensitivity, we determined that whereas levels...

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Detalles Bibliográficos
Autores principales: He, Feng, Agosto, Melina A., Anastassov, Ivan A., Tse, Dennis Y., Wu, Samuel M., Wensel, Theodore G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887901/
https://www.ncbi.nlm.nih.gov/pubmed/27245220
http://dx.doi.org/10.1038/srep26978