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Impact of HCV core gene quasispecies on hepatocellular carcinoma risk among HALT-C trial patients

Mutations at positions 70 and/or 91 in the core protein of genotype-1b, hepatitis C virus (HCV) are associated with hepatocellular carcinoma (HCC) risk in Asian patients. To evaluate this in a US population, the relationship between the percentage of 70 and/or 91 mutant HCV quasispecies in baseline...

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Detalles Bibliográficos
Autores principales: El-Shamy, Ahmed, Pendleton, Matthew, Eng, Francis J., Doyle, Erin H., Bashir, Ali, Branch, Andrea D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887904/
https://www.ncbi.nlm.nih.gov/pubmed/27246310
http://dx.doi.org/10.1038/srep27025