Skeletal muscle insulin resistance in hamsters with diabetes developed from obesity is involved in abnormal skeletal muscle LXR, PPAR and SREBP expression

Diabetic ‘lipotoxicity’ theory suggests that fat-induced skeletal muscle insulin resistance (FISMIR) in obesity induced by a high-fat diet (HFD), which leads to ectopic lipid accumulation in insulin-sensitive tissues, may play a pivotal role in the pathogenesis of type 2 diabetes. However, the chang...

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Detalles Bibliográficos
Autores principales: LI, GUO-SHENG, LIU, XU-HAN, ZHU, HUA, HUANG, LAN, LIU, YA-LI, MA, CHUN-MEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887951/
https://www.ncbi.nlm.nih.gov/pubmed/27284309
http://dx.doi.org/10.3892/etm.2016.3209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887951/
https://www.ncbi.nlm.nih.gov/pubmed/27284309
http://dx.doi.org/10.3892/etm.2016.3209

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