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TAK1 deficiency in dendritic cells inhibits adaptive immunity in SRBC‐immunized C57BL/6 mice

Dendritic cells (DCs) are important in the initiation of primary T‐cell responses, while transforming growth factor‐β (TGF‐β)‐activated kinase 1 (TAK1) is a critical regulator of DC survival and homeostasis. This study evaluated the T‐cell dependent antibody response (TDAR) to sheep red blood cells...

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Detalles Bibliográficos
Autores principales: Pan, Yao, Lei, Zhiming, Wei, Xuetao, Hao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887970/
https://www.ncbi.nlm.nih.gov/pubmed/27419057
http://dx.doi.org/10.1002/2211-5463.12062