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Autophagy enhancement contributes to the synergistic effect of vitamin D in temozolomide-based glioblastoma chemotherapy

Temozolomide (TMZ), an alkylating agent, is recommended as the initial treatment for high-grade glioblastoma. TMZ is widely used, but its short half-life and the frequency of tumor resistance limit its therapeutic efficacy. In the present study, the anticancer effect of vitamin D (VD) combined with...

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Detalles Bibliográficos
Autores principales: BAK, DONG-HO, KANG, SEONG HEE, CHOI, DU RI, GIL, MI NA, YU, KWANG SIK, JEONG, JI HEUN, LEE, NAM-SEOB, LEE, JE-HUN, JEONG, YOUNG-GIL, KIM, DONG KWAN, KIM, DO-KYUNG, KIM, JWA-JIN, HAN, SEUNG-YUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888049/
https://www.ncbi.nlm.nih.gov/pubmed/27313664
http://dx.doi.org/10.3892/etm.2016.3196