Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity

The polycomb repressive complex 1 (PRC1) is a multi-subunit complex that plays critical roles in the epigenetic modulation of gene expression. Here, we show that the PRC1 component polycomb group ring finger 6 (Pcgf6) is required to maintain embryonic stem cell (ESC) identity. In contrast to canonic...

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Detalles Bibliográficos
Autores principales: Yang, Chao-Shun, Chang, Kung-Yen, Dang, Jason, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888081/
https://www.ncbi.nlm.nih.gov/pubmed/27247273
http://dx.doi.org/10.1038/srep26899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888081/
https://www.ncbi.nlm.nih.gov/pubmed/27247273
http://dx.doi.org/10.1038/srep26899

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