ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice

Cannabidiol (CBD) is currently being investigated as a novel therapeutic for the treatment of CNS disorders like schizophrenia and epilepsy. ABC transporters such as P-glycoprotein (P-gp) and breast cancer resistance protein (Bcrp) mediate pharmacoresistance in these disorders. P-gp and Bcrp are exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Brzozowska, Natalia, Li, Kong M., Wang, Xiao Suo, Booth, Jessica, Stuart, Jordyn, McGregor, Iain S., Arnold, Jonathon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Drugs and Devices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888295/
https://www.ncbi.nlm.nih.gov/pubmed/27257556
http://dx.doi.org/10.7717/peerj.2081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888295/
https://www.ncbi.nlm.nih.gov/pubmed/27257556
http://dx.doi.org/10.7717/peerj.2081

Ejemplares similares