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Increasing the production of (R)-3-hydroxybutyrate in recombinant Escherichia coli by improved cofactor supply

BACKGROUND: In a recently discovered microorganism, Halomonas boliviensis, polyhydroxybutyrate production was extensive and in contrast to other PHB producers, contained a set of alleles for the enzymes of this pathway. Also the monomer, (R)-3-hydroxybutyrate (3HB), possesses features that are inter...

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Detalles Bibliográficos
Autores principales: Perez-Zabaleta, Mariel, Sjöberg, Gustav, Guevara-Martínez, Mónica, Jarmander, Johan, Gustavsson, Martin, Quillaguamán, Jorge, Larsson, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888404/
https://www.ncbi.nlm.nih.gov/pubmed/27245326
http://dx.doi.org/10.1186/s12934-016-0490-y