The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement

Human RNase 6 is a cationic secreted protein that belongs to the RNase A superfamily. Its expression is induced in neutrophils and monocytes upon bacterial infection, suggesting a role in host defence. We present here the crystal structure of RNase 6 obtained at 1.72 Å (1 Å=0.1 nm) resolution, which...

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Detalles Bibliográficos
Autores principales: Prats-Ejarque, Guillem, Arranz-Trullén, Javier, Blanco, Jose A., Pulido, David, Nogués, M. Victòria, Moussaoui, Mohammed, Boix, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888456/
https://www.ncbi.nlm.nih.gov/pubmed/27013146
http://dx.doi.org/10.1042/BCJ20160245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888456/
https://www.ncbi.nlm.nih.gov/pubmed/27013146
http://dx.doi.org/10.1042/BCJ20160245

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