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Non-canonical dynamic mechanisms of interaction between the p66Shc protein and Met receptor

Met receptor tyrosine kinase (RTK) is known to bind to the three distinct protein isoforms encoded by the ShcA (Shc) gene. Structure–function studies have unveiled critical roles for p52Shc-dependent signalling pathways in Met-regulated biological functions. The molecular basis of the interaction be...

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Detalles Bibliográficos
Autores principales: Landry, Mélissa, Pomerleau, Véronique, Saucier, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888465/
https://www.ncbi.nlm.nih.gov/pubmed/27048591
http://dx.doi.org/10.1042/BCJ20160249