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Reduction of cytosolic phospholipase A(2)α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal multifactorial neurodegenerative disease characterized by selective death of motor neurons in the cortex, brainstem, and spinal cord. Cytosolic phospholipase A(2) alpha (cPLA(2)α) upregulation and activation in the spinal cord of patients wi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888471/ https://www.ncbi.nlm.nih.gov/pubmed/27250836 http://dx.doi.org/10.1186/s12974-016-0602-y |