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Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres
BACKGROUND: Chromatin containing the histone variant CENP-A (CEN chromatin) exists as an essential domain at every centromere and heritably marks the location of kinetochore assembly. The size of the CEN chromatin domain on alpha satellite DNA in humans has been shown to vary according to underlying...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888493/ https://www.ncbi.nlm.nih.gov/pubmed/27252782 http://dx.doi.org/10.1186/s13072-016-0071-7 |