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Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres

BACKGROUND: Chromatin containing the histone variant CENP-A (CEN chromatin) exists as an essential domain at every centromere and heritably marks the location of kinetochore assembly. The size of the CEN chromatin domain on alpha satellite DNA in humans has been shown to vary according to underlying...

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Detalles Bibliográficos
Autores principales: Ross, Justyne E., Woodlief, Kaitlin Stimpson, Sullivan, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888493/
https://www.ncbi.nlm.nih.gov/pubmed/27252782
http://dx.doi.org/10.1186/s13072-016-0071-7