Implications of using whole genome sequencing to test unselected populations for high risk breast cancer genes: a modelling study

BACKGROUND: The decision to test for high risk breast cancer gene mutations is traditionally based on risk scores derived from age, family and personal cancer history. Next generation sequencing technologies such as whole genome sequencing (WGS) make wider population testing more feasible. In the UK...

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Detalles Bibliográficos
Autores principales: Warren-Gash, Charlotte, Kroese, Mark, Burton, Hilary, Pharoah, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888520/
https://www.ncbi.nlm.nih.gov/pubmed/27252788
http://dx.doi.org/10.1186/s13053-016-0052-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888520/
https://www.ncbi.nlm.nih.gov/pubmed/27252788
http://dx.doi.org/10.1186/s13053-016-0052-7

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