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Implications of using whole genome sequencing to test unselected populations for high risk breast cancer genes: a modelling study
BACKGROUND: The decision to test for high risk breast cancer gene mutations is traditionally based on risk scores derived from age, family and personal cancer history. Next generation sequencing technologies such as whole genome sequencing (WGS) make wider population testing more feasible. In the UK...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888520/ https://www.ncbi.nlm.nih.gov/pubmed/27252788 http://dx.doi.org/10.1186/s13053-016-0052-7 |