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Endogenous analgesia mediated by CD4(+) T lymphocytes is dependent on enkephalins in mice

BACKGROUND: T cell-derived opioids play a key role in the control of inflammatory pain. However, the nature of opioids produced by T cells is still matter of debate in mice. Whereas β-endorphin has been found in T lymphocytes by using antibody-based methods, messenger RNA (mRNA) quantification shows...

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Detalles Bibliográficos
Autores principales: Basso, Lilian, Boué, Jérôme, Mahiddine, Karim, Blanpied, Catherine, Robiou-du-Pont, Sébastien, Vergnolle, Nathalie, Deraison, Céline, Dietrich, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888630/
https://www.ncbi.nlm.nih.gov/pubmed/27245576
http://dx.doi.org/10.1186/s12974-016-0591-x