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Endogenous analgesia mediated by CD4(+) T lymphocytes is dependent on enkephalins in mice
BACKGROUND: T cell-derived opioids play a key role in the control of inflammatory pain. However, the nature of opioids produced by T cells is still matter of debate in mice. Whereas β-endorphin has been found in T lymphocytes by using antibody-based methods, messenger RNA (mRNA) quantification shows...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888630/ https://www.ncbi.nlm.nih.gov/pubmed/27245576 http://dx.doi.org/10.1186/s12974-016-0591-x |