Cargando…
Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels
BACKGROUND: Myocardial infarction (MI) is a major cause of heart failure. The carboxypeptidase cathepsin A is a novel target in the treatment of cardiac failure. We aim to show that recently developed inhibitors of the protease cathepsin A attenuate post-MI heart failure. METHODS: Mice were subjecte...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888645/ https://www.ncbi.nlm.nih.gov/pubmed/27246731 http://dx.doi.org/10.1186/s12967-016-0907-8 |