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Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells

BACKGROUND: Hematopoietic stem cell renewal and differentiation are regulated through epigenetic processes. The conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5hmC) by ten-eleven-translocation enzymes provides new insights into the epigenetic regulation of gene expression during develo...

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Detalles Bibliográficos
Autores principales: Tekpli, Xavier, Urbanucci, Alfonso, Hashim, Adnan, Vågbø, Cathrine B., Lyle, Robert, Kringen, Marianne K., Staff, Anne Cathrine, Dybedal, Ingunn, Mills, Ian G., Klungland, Arne, Staerk, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888655/
https://www.ncbi.nlm.nih.gov/pubmed/27252783
http://dx.doi.org/10.1186/s13072-016-0070-8